Cullen returns to the Mormon Fort only to discover it abandoned following a brutal smallpox epidemic. Desperate to find his lost family, Cullen wrestles with a difficult decision when he is poached by the Central Pacific Railroad.
After dealing with the Cheyenne, Bohannon completes an important construction milestone. Mr. Toole rises from the dead to spoil Elam and Eva’s future plans. The McGinnes Brothers foresee changing fortunes. Durant issues a dire warning to Bohannon.
Lily accomplanies Durant to Chicago, where he continues dealings with Senator Crane while she attends to matters relating to the death of her husband. Meanwhile, Cullen gets swepped up in frictions between Mr. Toole and Elam.